163 research outputs found

    The Effect of Clay Pozzolana-Cement-Composite on the Strength Development of a Hydraulic Backfill

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    The study sought to investigate the potential application of clay pozzolana as a supplement for cement in hydraulic backfill, using classified tailings from AngloGold Ashanti, Obuasi Mine. The percentage of the Portland cement that could be substituted with the clay pozzolana to produce backfill with best strength was determined. 10%, 25%, 30%, 35% and 40% of the ordinary Portland cement were replaced with clay pozzolana and then mixed with tailings and water. The slurry produced was cast into cylindrical specimen of 50mm diameter by 120mm high and tested for compressive strength after curing for 7, 14, 21, 28 and 56 days. The results indicate that, clay pozzolana-cement composite has potential for application in hydraulic back fill production without increased risk to safety and dilution. It was noted that hydraulic backfill with 10%, 25%, 30% and 35% of the ordinary portland cement replaced with clay pozzolana had strengths greater than those obtained for ordinary portland cement alone. Ten percent (10%) pozzolana content gave the maximum strength followed by 25% pozzolana. It is recommended that for safety and economic considerations, the cement content should be replaced by 25% pozzolana in the production of backfills. Keywords: Hydraulic Backfill, Portland Cement, Clay Pozzolana, Unconfined Compressive Strengt

    Examining the effects of HIV self-testing compared to standard HIV testing services in the general population: A systematic review and meta-analysis

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    BACKGROUND: We updated a 2017 systematic review and compared the effects of HIV self-testing (HIVST) to standard HIV testing services to understand effective service delivery models among the general population. METHODS: We included randomized controlled trials (RCTs) comparing testing outcomes with HIVST to standard testing in the general population and published between January 1, 2006 and June 4, 2019. Random effects meta-analysis was conducted and pooled risk ratios (RRs) were reported. The certainty of evidence was determined using the GRADE methodology. FINDINGS: We identified 14 eligible RCTs, 13 of which were conducted in sub-Saharan Africa. Support provided to self-testers ranged from no/basic support to one-on-one in-person support. HIVST increased testing uptake overall (RR:2.09; 95% confidence interval: 1.69-2.58; INTERPRETATION: HIVST appears to be safe and effective among the general population in sub-Saharan Africa with a range of delivery models. It identified and linked additional people with HIV to care. These findings support the wider availability of HIVST to reach those who may not otherwise access testing

    Maintaining relevance in HIV systematic reviews: an evaluation of Cochrane reviews

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    Background Research turnover in the HIV field is rapid, and as a result, maintaining high-quality, up-to-date, and relevant systematic reviews is a challenge. One approach is to frequently update published reviews. Methods We evaluated the methods and relevance of all HIV systematic reviews and protocols published in the Cochrane Library over a 16-year period (2000–2016) to determine the need to update published reviews or complete of reviews in progress. Results Of 148 published reviews and protocols, 129 (87%) were identified as not for updating or progression to publication, mostly due to research questions which were either entirely outdated or addressed questions in an outdated manner (N = 89; 60%); this was anticipated for older reviews, but was found also to be the case for recent publications. Some research questions were also inadequately conceptualized, particularly when complex pragmatic trials or behavioral interventions were included. Conclusions We suggest that authors clearly characterize interventions and synthesis approaches in their review protocols. In research fields, such as HIV, where questions change frequently, systematic reviews and protocols should be regularly re-evaluated to ensure relevance to current questions. This process of re-evaluation should be incorporated into the methods of living systematic reviews

    A systematic review and network meta-analyses to assess the effectiveness of human immunodeficiency virus (HIV) self-testing distribution strategies

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    BACKGROUND: We conducted a systematic review and network meta-analysis to identify which human immunodeficiency virus (HIV) self-testing (HIVST) distribution strategies are most effective. METHODS: We abstracted data from randomized controlled trials and observational studies published between 4 June 2006 and 4 June 2019. RESULTS: We included 33 studies, yielding 6 HIVST distribution strategies. All distribution strategies increased testing uptake compared to standard testing: in sub-Saharan Africa, partner HIVST distribution ranked highest (78% probability); in North America, Asia, and the Pacific regions, web-based distribution ranked highest (93% probability), and facility based distribution ranked second in all settings. Across HIVST distribution strategies HIV positivity and linkage was similar to standard testing. CONCLUSIONS: A range of HIVST distribution strategies are effective in increasing HIV testing. HIVST distribution by sexual partners, web-based distribution, as well as health facility distribution strategies should be considered for implementation to expand the reach of HIV testing services

    Suicidality and depression among adult patients admitted in general medical facilities in Kenya

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    <p>Abstract</p> <p>Aim</p> <p>To document Beck Depression Inventory (BDI) II suicidal symptoms among patients admitted to Kenyan non-psychiatric general medical facilities</p> <p>Methods</p> <p>All consenting adults admitted within a period of 4 weeks at 10 general medical facilities in Kenya were interviewed for suicidal symptoms and depression using the BDI-II.</p> <p>Results</p> <p>In all, 2,780 patients responded to item 9 (suicidal symptoms of the BDI-II). The prevalence of all BDI-II suicidal symptoms combined was 10.5%. Thoughts of 'killing oneself but have not carried them out' accounted for 9% of the suicidal symptoms. The younger age group had the highest prevalence of suicidal symptoms and the oldest age group had the least prevalence of suicidal symptoms. The more depressed the patients were on the overall BDI-II score, the higher the prevalence of suicidal symptoms.</p> <p>Conclusion</p> <p>On average 1 out of 10 of the patients had suicidal symptoms, more so in younger than the older people and in the more depressed. These symptoms had not been clinically recognised and therefore not managed. This calls for clinical practice that routinely enquires for suicidal symptoms in general medical wards.</p

    Building a Small Cinema: Resisting Neoliberal Colonization in Liverpool

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    In its stated aim of “creating cinemas not supermarkets,” the Small Cinema project voiced its alterity to the recent redevelopment of Liverpool’s city center and those of other former industrial cities throughout the Midlands and the north of the UK. These regeneration projects addressed the problem of a shrinking manufacturing base by replacing them with service industries, a move which has entailed the privatization of vast tracts of public space. Conversely, the building, functioning, and general praxis of the Small Cinema project suggests a mode of practice that more accurately fits within the paradigm of a collaborative commons than a capitalist marketplace. The project’s exemption from market criteria grants it the freedom to pursue public over private goods, thereby constituting a point of resistance to the ongoing neoliberalization of the city and changes to government policy that make it increasingly difficult for non-profit projects to exist. Historically speaking, cinemas have been accessible to the working class in a way that other artistic media have not. However, while the history of film as a tool for political subversion is well documented, less attention has been paid to the physical construction of independent cinematic space, its programming/running, and its potential as a node of resistance to neoliberal colonization. This paper uses the case study of the Small Cinema project in Liverpool as a means by which to understand how cinematic spaces can counteract the effects of policies that continue to have such a detrimental impact on the arts and education, as well as social health and well-being

    A systematic review of the relationship between rumination and suicidality

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    Rumination has been persistently implicated in the etiology of hopelessness and depression: proximal predictors of suicidality. As a result, research has started to examine the role of rumination in suicidality. This systematic review aims to: (i) provide a concise synopsis of the current progress in examining the relationship between rumination and suicidality; and (ii) highlight areas for future research. To this end, a search of the international literature was conducted using the three main psychological and medical databases (Psych Info [1887-October 2007], Medline [1966-October 2007] and Web of Knowledge [1981-October 2007]). Eleven studies were identified providing evidence, with one exception, of a relationship between rumination and suicidality. This systematic review has highlighted a considerable dearth of studies, specifically of case-control and prospective, clinical studies, in the worldwide literature. Key areas for future research are discussed

    A systematic review and network meta-analyses to assess the effectiveness of HIV self-testing distribution strategies.

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    BACKGROUND: We conducted a systematic review and network meta-analysis to identify which HIV self-testing (HIVST) distribution strategies are most effective. METHODS: We abstracted data from randomized controlled trials and observational studies published between June 4, 2006 and June 4, 2019. RESULTS: We included 33 studies, yielding six HIVST distribution strategies. All distribution strategies increased testing uptake compared to standard testing: in sub-Saharan Africa, partner HIVST distribution ranked highest (78% probability); in North America, Asia and the Pacific regions, web-based distribution ranked highest (93% probability), and facility based distribution ranked second in all settings. Across HIVST distribution strategies HIV positivity and linkage was similar to standard testing. CONCLUSION: A range of HIVST distribution strategies are effective in increasing HIV testing. HIVST distribution by sexual partners, web-based distribution, as well as health facility distribution strategies should be considered for implementation to expand the reach of HIV testing services
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